12(R)-HETE
CAS No. : 82337-46-0
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| Cat. No. : | HY-124404 |
| M.Wt: | 320.47 |
| Formula: | C20H32O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
12(R)-HETE is a metabolite of Arachidonic acid, AA (HY-109590) and can be found in skin from psoriatic lesions. 12(R)-HETE induces lymphocytes chemotaxis, stimulates calcium mobilization and chemotaxis in neutrophils via the BLT1 receptor, activates the aryl hydrocarbon receptor, and inhibits Na+/K+ ATPase activity in the corneal epithelium[1][2][3][4].
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