CMK
CAS No. : 821794-90-5
Price and Availability of
CAS No. : 821794-90-5
| Size | Price | Stock |
|---|---|---|
| 2mg | $120 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $300 | In-stock |
| 25mg | $432 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-52101 |
| M.Wt: | 358.82 |
| Formula: | C18H19ClN4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 150 mg/mL (ultrasonic) |
Introduction of
821794-90-5
:
CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. In Vitro: CMK inhibits the growth of Cdc5 (L158G) with IC50 of 36 nM, greater than 30 μM for wild type Cdc5. CMK exhibits a concentration-dependent first cell cycle mitotic arrest in the cdc5-as1 strain with an IC50 of 1.1 μM. CMK inhibition of Cdc5 (L158G) leads to a first cell cycle anaphase arrest and delay in anaphase spindle migration[1].
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