10Z-Hymenialdisine


CAS No. : 82005-12-7

(Synonyms: (Z)-Hymenialdisine; Hymenialdisine)

82005-12-7
Price and Availability of CAS No. : 82005-12-7
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Cat. No. : HY-N6794
M.Wt: 324.13
Formula: C11H10BrN5O2
Purity: >98 %
Solubility: DMSO : 3.24 mg/mL (ultrasonic;warming)
Introduction of 82005-12-7 :

10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities[1]. In Vitro: 10Z-Hymenialdisine displays a moderate effect on (ARK5, VEGFR-2, SAK and PDGFR) protein kinases. 10Z-Hymenialdisine shows a potent inhibition of RAF/MEK-1/MAPK cascade with an IC50 value of 6 nM[1].

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