CB7993113
CAS No. : 819827-50-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $468 | In-stock |
| 50mg | $750 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-111450 |
| M.Wt: | 364.15 |
| Formula: | C15H10BrNO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively[1].
In Vitro:CB7993113 exhibits no toxicity when added at concentrations at least up to 20 μM to several human cells including HepG2 hepatoma cells, BP1, D3, Hs578T, or MDA-MB-231 breast cancer cells, and primary human-induced pluripotent stem cells[1].
CB7993113 significantly reduces the invasive phenotype of ER-/PR-/HER2- breast cancer cells in vitro[1].
In Vivo:CB7993113 effectively blocks acute, 50 mg/kg DMBA-induced hepatic CYP1A1 induction and bone marrow toxicity in vivo[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- CB7993113
- Cat. No.:
- HY-111450
- Quantity:
Your information is safe with us.