Ganoderic acid A
CAS No. : 81907-62-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $125 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $320 | In-stock |
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| Cat. No. : | HY-N1447 |
| M.Wt: | 516.67 |
| Formula: | C30H44O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic);Ethanol : ≥ 50 mg/mL |
Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
In Vitro: A lower doses of Ganoderic acid A enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma[1].
Ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression[2].
Ganoderic acid Ainhibits proliferation, viability, ROS, DPPH, and analyzed the expression of SOD1, SOD2, and SOD3 by Real time PCR in a PC-3 cell in a dose-dependent manner[3].
Ganoderic acid A effectively inhibites the proliferation of human osteosarcoma HOS and MG-63 cells in a dose-dependent manner, and induced obvious cell apoptosis in both cells[4].
In Vivo: Ganoderic acid A treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver[4].
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