14,15-Epoxyeicosatrienoic acid
CAS No. : 81276-03-1
(Synonyms: 14,15-EET)
| Size | Price | Stock |
|---|---|---|
| 312.04 μM * 500 μL in Ethanol | $560 | Get quote |
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| Cat. No. : | HY-113489 |
| M.Wt: | 320.47 |
| Formula: | C20H32O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2].
In Vitro:14,15-Epoxyeicosatrienoic acid (0-10 μM) promotes Aβ uptake in primary astrocyte cultures[1].
In Vivo:14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) inhibits platelet aggregation in mouse cerebral arterioles[2].
14,15-Epoxyeicosatrienoic acid (200 ng/ml) infusion into the hippocampus reversed Aβ deposition in the brains of 6-month-old male FAD mice[1].
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