Boc-NH-PEG4-CH2CH2NH2
CAS No. : 811442-84-9
| Size | Price | Stock |
|---|---|---|
| 100mg | $18 | In-stock |
| 250mg | $28 | In-stock |
| 1g | $42 | In-stock |
| 5g | $181 | In-stock |
| 10g | $361 | In-stock |
| 25g | $649 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-W008352 |
| M.Wt: | 336.42 |
| Formula: | C15H32N2O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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