N-Nonyldeoxynojirimycin
CAS No. : 81117-35-3
(Synonyms: NN-DNJ; Nonyl-DNJ)
| Size | Price | Stock |
|---|---|---|
| 5mg | $170 | In-stock |
| 10mg | $270 | In-stock |
| 25mg | $540 | In-stock |
| 50mg | $860 | In-stock |
| 100mg | $1380 | In-stock |
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| Cat. No. : | HY-107532 |
| M.Wt: | 289.41 |
| Formula: | C15H31NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
N-Nonyldeoxynojirimycin (NN-DNJ) is a deoxynojirimycin derivative with a hydrophobic long chain. N-Nonyldeoxynojirimycin is an orally active inhibitor of acid α-glucosidase (IC50: 0.42 μM) and α-1,6-glucosidase (IC50: 8.4 μM). N-Nonyldeoxynojirimycin has activities of inhibiting glycogen breakdown, anti-virus and anti-tumor. N-Nonyldeoxynojirimycin also has insecticidal effects, with an LD50 of 5 mM for adults of Bemisia tabaci[1][2][3][4].
In Vitro:N-Nonyldeoxynojirimycin (0-200 μM; 3 days) inhibits the secretion of infectious bovine viral diarrhea virus (BVDV) in MDBK cells with an IC50 of 2.5 μM[1].
In Vivo:N-Nonyldeoxynojirimycin (10-250 mg/kg; dietary administration; 1-120 days) can induce glycogen accumulation in the liver and skeletal muscles of mice[2].
N-Nonyldeoxynojirimycin (dietary administration) reduces tumor growth and ganglioside content with fewer side effects compared to Miglustat (HY-17020) in C57BL/6 mice bearing CT-2A tumors[3].
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