YC137
CAS No. : 810659-53-1
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| Cat. No. : | HY-123244 |
| M.Wt: | 511.57 |
| Formula: | C24H21N3O6S2 |
| Purity: | >98 % |
| Solubility: |
YC137 is a potent Bcl-2 antagonist with Kis of 1.3 μM and >100 μM for Bcl-2 and Bcl-xL when assayed in Bis-Tris buffer, respectively. YC137 inhibits the binding of the Bid BH3 peptide to Bcl-2, thus disrupting an interaction essential for the antiapoptotic activity of Bcl-2. YC137 selectively induces apoptosis of Bcl-2-dependent cells. YC137 has the potential for breast cancer research[1][2].
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