Telenzepine
CAS No. : 80880-90-6
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| Cat. No. : | HY-B1789 |
| M.Wt: | 370.47 |
| Formula: | C19H22N4O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Telenzepine is an antimuscarinic agent with Kis of 0.94 nM (M1 mAChR) and 17.8 nM (M2 mAChR) binding to muscarinic receptors. Telenzepine effectively blocks synaptic transmission promoted by muscarinic or M1 receptor agonists. Thus, Telenzepine can reduce the amplitude of extracellular slow excitatory postsynaptic potentials (EC50=38 nM) and slow inhibitory postsynaptic potentials (EC50=253 nM)[1].
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