Grossamide
CAS No. : 80510-06-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $546 | In-stock |
| 5mg | $1365 | In-stock |
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| Cat. No. : | HY-N3979 |
| M.Wt: | 624.68 |
| Formula: | C36H36N2O8 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Grossamide is a natural product that can be isolated from fructus cannabis, the dried fruit of Cannabis sativa L.. Grossamide has anti-neuroinflammatory effects[1].
In Vitro: Grossamide downregulates LPS-mediated production of inflammatory molecules[1].
Grossamide (0-20 μM, 1 h) inhibits the mRNA levels of TNF-α and IL-6 in a dose-dependent manner, inhibits LPS-induced NF-κB activation, and inhibits LPS-induced TLR4 and MyD88 expression without cytotoxicity[1].
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