O-Desmethyltramadol


CAS No. : 80456-81-1

80456-81-1
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Cat. No. : HY-109054
M.Wt: 249.35
Formula: C15H23NO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 80456-81-1 :

O-Desmethyltramadol is the main active metabolite of tramadol (Tramadol) and can cross the blood-brain barrier. O-Desmethyltramadol mainly exerts its analgesic effect by activating the µ-opioid receptor (µ-OR)[1][2]. In Vitro: O-Desmethyltramadol can be metabolized from Tramadol through the cytochrome P450 (CYP) 2D6 enzyme[1].

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