Yonkenafil (hydrochloride)
CAS No. : 804519-64-0
(Synonyms: Tunodafil (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $380 | In-stock |
| 10mg | $610 | In-stock |
| 25mg | $1150 | In-stock |
| 50mg | $1800 | In-stock |
| 100mg | $2850 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-125095 |
| M.Wt: | 524.08 |
| Formula: | C24H34ClN5O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Yonkenafil (Tunodafil) hydrochloride, a novel phosphodiesterase 5 (PDE5) inhibitor, is effective in reducing cerebral infarction, neurological deficits, edema, and neuronal damage in the infarcted area. Yonkenafil (Tunodafil) hydrochloride may improve cognitive function by modulating neurogenesis and has a potential therapeutic effect on Alzheimer's disease[1].
In Vivo: Yonkenafil (Tunodafil) hydrochloride (4-32 mg/kg, i.v. daily for 7 days) improves behavioral outcomes after stroke and reduces cerebral infarct volume, inhibits neuronal apoptosis, and significantly enhances synaptic function in ischemic brain by modulating the expression of BDNF/TrkB and NGF/TrkA[1].
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