Furafylline
CAS No. : 80288-49-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $150 | In-stock |
| 5mg | $300 | In-stock |
| 10mg | $444 | In-stock |
| 25mg | $755 | In-stock |
| 50mg | $1057 | In-stock |
| 100mg | $1480 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-107204 |
| M.Wt: | 260.25 |
| Formula: | C12H12N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (ultrasonic) |
Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC50 of 0.07 μM. IC50 & Target: IC50: 0.07 μM (human cytochrome P450IA2)[1] In Vivo: Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC50 of 0.07 μM in kinase experiment. Furafylline is a methylxanthine derivative that is introduced as a long-acting replacement for theophylline in the treatment of asthma. Administration of Furafylline is associated with an elevation in plasma levels of caffeine, due to inhibition of caffeine oxidation, a reaction catalysed by one or more hydrocarbon-inducible isoenzymes of P450. Furafylline has either very little or no effect on human monooxygenase activities catalysed by other isoenzymes of P450, including P4501ID1, P4501IC, P450IIIA[1].
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- Furafylline
- Cat. No.:
- HY-107204
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