Antibiotic A-33853


CAS No. : 80148-45-4

80148-45-4
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Cat. No. : HY-14366
M.Wt: 391.33
Formula: C20H13N3O6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 80148-45-4 :

Antibiotic A-338533, an antibiotic, can be isolated from Streptomyces strain. Antibiotic A-338533 has anti-bacterial activity against Staphylococcus aureus, Mycoplasma gallisepticum with MIC values of 2 μg/mL and ≤1.56 μg/mL, respectively[1]. In Vitro:Antibiotic A-33853 shows inhibitory effect against the protozoan organism Eimeria tenella (major causative or ganism of coccidiosis), and inhibits Trichomonas vaginalis with an MIC value of <0.975 ug/mL[1].
In Vivo:Antibiotic A-33853 (60 mg/kg; s.c.; single dose) is inactive against Mycoplasma gallisepticum in chicks in vivo[1].
Antibiotic A-33853 (70 mg/kg; s.c.; twice doses) is ineffective against S. aureus in mice in vivo[1].
Antibiotic A-33853 has an acute toxic dose with a LD50 value >300 mg/kg (i.p.) on mice model[1].

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