(S)-Remoxipride
CAS No. : 80125-14-0
(Synonyms: (-)-Remoxipride)
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| Cat. No. : | HY-101313 |
| M.Wt: | 371.27 |
| Formula: | C16H23BrN2O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
(S)-Remoxipride ((-)-Remoxipride) is a selective dopamine D2-receptor antagonist with an IC50 value of 1.57 μM. (S)-Remoxipride can be used for the research of psychotic disorder[1]. In Vitro:(S)-Remoxipride (1-100 μM; 20 min) shows binding efficiency with IC50s of ＞100, 1.57 and 42 μM for dopamine D1, dopamine D2 and α1-Adrenoccptor, respectively[1]. In Vivo:(S)-Remoxipride (0.1-100 μM/kg; i.p. 60 min prior to apomorphine) blockades apomorphine-induced behaviors s in rats and vomiting in dogs[1]. (S)-Remoxipride (0.1-10 mg/kg; i.p. 30 min prior to apomorphine) displaces [3H]spiperone from both striatal and extra-striatal areas[1].
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