Halazone


CAS No. : 80-13-7

80-13-7
Price and Availability of CAS No. : 80-13-7
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Cat. No. : HY-B1386
M.Wt: 270.09
Formula: C7H5Cl2NO4S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 80-13-7 :

Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2]. In Vitro: Halazone is chemically closely related to Chloramine-T, the nitrogen atom is linked with two instead of one chlorine atom and, certainly more important here, a methyl group is replaced by a carboxyl group. The effect of Halazone on the sodium current is studied in voltage-clamped single nerve fibers of the frog. The oxidant Halazone drastically inhibits inactivation[1].

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