Loratadine


CAS No. : 79794-75-5

(Synonyms: Loratidine; SCH 29851)

79794-75-5
Price and Availability of CAS No. : 79794-75-5
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Cat. No. : HY-17043
M.Wt: 382.88
Formula: C22H23ClN2O2
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 79794-75-5 :

Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators. IC50 & Target: IC50 value: 32 uM (H1-receptor) In Vitro: Loratadine is an antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.

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