Bulaquine


CAS No. : 79781-00-3

(Synonyms: CDRI 80/53; Elubaquine)

79781-00-3
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Cat. No. : HY-106866
M.Wt: 369.46
Formula: C21H27N3O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 79781-00-3 :

Bulaquine (CDRI 80/53) is a potent antimalarial agent which is an analogue of Primaquine (HY-12651A). Bulaquine affects multiple metabolism pathways and shows inhibition effect on Plasmodium cynomolgi infection. Bulaquine can be used for the research of malaria[1][2][3]. In Vivo:Bulaquine (40 mg/kg; p.o. once) affects multiple pathways in vivo[1].
Bulaquine (1.25 mg/kg; once daily; for 7 days) shows 100% curative anti-relapse activity with a primaquine index of 0.8 for rhesus monkeys with Plasmodium cynomolgi B infection[2].

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