Midaglizole (hydrochloride)
CAS No. : 79689-25-1
(Synonyms: (±)-DG5128; DG5128)
| Size | Price | Stock |
|---|---|---|
| 5mg | $357 | In-stock |
| 10mg | $519 | In-stock |
| 25mg | $883 | In-stock |
| 50mg | $1236 | In-stock |
| 100mg | $1731 | In-stock |
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| Cat. No. : | HY-U00165 |
| M.Wt: | 324.25 |
| Formula: | C16H19Cl2N3 |
| Purity: | >98 % |
| Solubility: | DMSO : 500 mg/mL (ultrasonic;warming;heat to 60°C) |
Midaglizole hydrochloride ((±)-DG5128, DG5128) is a potent α2-adrenoceptor antagonist. Midaglizole hydrochloride is a hypoglycemic agent. Midaglizole hydrochloride increases blood pressure and reduces blood glucose levels in vivo[1][2][3].
In Vitro:Midaglizole hydrochloride stimulates insulin release with the EC50 values of 200 nM, 24 µM for rat islets and MIN6 β-cell line, respectively[3].
In Vivo:Midaglizole hydrochloride (3, 30 mg/kg; i.v.) increases blood pressure in rats[1].
Midaglizole hydrochloride (0.2, 1, 2 mg/kg; infusion) reduces blood glucose levels in dags[2].
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