Fleroxacin
CAS No. : 79660-72-3
(Synonyms: RO 23-6240; AM-833)
| Size | Price | Stock |
|---|---|---|
| 500mg | $30 | In-stock |
| 1g | $50 | In-stock |
| 5g | $120 | In-stock |
| 10g | $180 | In-stock |
| 25g | $344 | In-stock |
| 50g | $517 | In-stock |
| 100g | $750 | In-stock |
| 200 g | Get quote | |
| 500 g | Get quote | |
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| Cat. No. : | HY-B0414 |
| M.Wt: | 369.34 |
| Formula: | C17H18F3N3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL;H2O : 33.33 mg/mL (ultrasonic;adjust pH to 11 with NaOH);0.1 M NaOH : 9.17 mg/mL (ultrasonic;adjust pH to 12 with NaOH) |
Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. In Vivo: Fleroxacin (Ro 23-6240) is a new trifluorinated quinolone exhibiting high activity against a broad spectrum of gram-negative and gram-positive bacteria. Fleroxacin is characterized pharmacokinetically by a long elimination half-life (9 to 10 h) and high concentrations in plasma (e.g., maximum concentration of 2.3 micrograms/ml after an oral dose of 200 mg)[1]. Fleroxacin (Ro 23-6240) is effective against Haemophilus ducreyi in vitro. Fleroxacin (Ro 23-6240), 200 or 400 mg as a single oral dose, is efficacious therapy for microbiologically proven chancroid in patients who do not have concurrent HIV-1 infection. Among HIV-1-infected men, a single dose of 200 or 400 mg of fleroxacin is inadequate therapy for chancroid[2][3].
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