AS8351
CAS No. : 796-42-9
(Synonyms: NSC51355)
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $80 | In-stock |
| 50mg | $250 | In-stock |
| 100mg | $450 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-100744 |
| M.Wt: | 291.30 |
| Formula: | C17H13N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 150 mg/mL (ultrasonic;warming) |
AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells[1]. IC50 & Target: KDM5B[1] In Vitro: AS8351 affects epigenetic modifications by competing with α-ketoglutarate (α-KG) for chelating iron [Fe(II)] in certain epigenetic enzymes, such as the JmjC domain-containing histone demethylases (JmjC-KDMs) that require α-KG and iron as co-factors[2].
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