Euptox A
CAS No. : 79491-71-7
(Synonyms: 9-Oxo-10,11-dehydroageraphorone)
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| Cat. No. : | HY-N2802 |
| M.Wt: | 232.32 |
| Formula: | C15H20O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells[1].
In Vitro:Euptox A (0-2 μg/mL, 48 h) effectively inhibits the proliferation of HeLa cells[1].
Euptox A (0-50 μg/mL, 24 h) arrests the cell cycle transition from S to G2/M phase[1].
Euptox A presents significantly antitumor activity against the human lung cancer A549, HeLa and Hep-2 cell lines in vitro in a dose-dependent manner[1].
Euptox A exhibits highly acaricidal activity for S.scabiei and P. cuniculi in vitro[1].
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