Cefixime
CAS No. : 79350-37-1
(Synonyms: FR-17027; FK-027; CL-284635)
| Size | Price | Stock |
|---|---|---|
| 10mg | $29 | In-stock |
| 25mg | $53 | In-stock |
| 50mg | $80 | In-stock |
| 100mg | $120 | In-stock |
| 250mg | $210 | In-stock |
| 500mg | $310 | In-stock |
| 1g | $460 | In-stock |
| 5g | $1150 | In-stock |
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| Cat. No. : | HY-B1381 |
| M.Wt: | 453.45 |
| Formula: | C16H15N5O7S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections[1][2].
In Vitro: Cefixime shows great antibacterial activity against clinical isolates of Salmonella typhi, with a MIC90 value of 0.25 μg/mL, and is also active against β-lactamase producing Amoxicillin (HY-B0467A)-resistant strains[3].
Cefixime is also active against Enterobacteriaceae, such as Haemophilus influenzae, and Neisseria gonorrhoeae[6].
In Vivo: Cefixime (0.75-60 mg/kg, oral gavage) reduces the bacterial burden in mice challenged with FA1090 (ESC-susceptible strain)[4].
cefixime (50 or 150 mg/kg, oral gavage) changes the structure and abundance of the gut microbiota of C57BL/6J mice, specifically, a reduction in the diversities of the microbial community and decreasing to one preponderant Firmicutes phylum[5].
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