Cyclosporin
CAS No. : 79217-60-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $25 | In-stock |
| 10mg | $35 | In-stock |
| 25mg | $60 | In-stock |
| 50mg | $110 | In-stock |
| 100mg | $155 | In-stock |
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| Cat. No. : | HY-100731 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes[1].
In Vitro: Cyclosporin (0-2500 nM; Ppia-/- cells) inhibits proliferation of Ppia+/+ or Ppia+/- splenocytes to a similar degree, with an IC50 value of 25 nM, the IC50 of Ppia-/- splenocytes has at least 10-fold higher[1].
Cyclosporin (0-750 nM; Ppia-/- cells) inhibits gene expression in Ppia-/- cells[1].
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