Polygalasaponin XXXI
CAS No. : 79103-90-5
(Synonyms: Onjisaponin F)
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| 5mg | $360 | In-stock |
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| Cat. No. : | HY-N2216 |
| M.Wt: | 1589.67 |
| Formula: | C75H112O36 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection[1].
In Vitro: Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG Ab titers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA Ab titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus[1].
Polygalasaponin XXXI (Onjisaponin F) (1 or 10 µg/mL) also induces ChAT mRNA level in rat basal forebrain cells[2].
In Vivo: Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin F) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice[1].
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