Daltroban
CAS No. : 79094-20-5
(Synonyms: BM-13505; SKF 96148)
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| 1mg | $110 | In-stock |
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| Cat. No. : | HY-121018 |
| M.Wt: | 353.82 |
| Formula: | C16H16ClNO4S |
| Purity: | >98 % |
| Solubility: | DMSO : 22 mg/mL (ultrasonic;warming) |
Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist. Daltroban increase intracellular calcium in vascular smooth muscle cells. Daltroban shows protective effect in reperfusion injury[1][2].
In Vivo: Daltroban (BM-13505) (1 mg/kg; i.v.; per hour) exerts protective effect in reperfusion injury following acute myocardial ischemia in cats[2].
In comparison with vehicle (physiological saline)-treated cats, Daltroban (20 mg/kg per hour i.v.) reduces the ischaemia-induced rise in the ST segment and prevented the development of a Q-wave in the ECG during reperfusion. Daltroban protects the myocardium from ischaemic injury and that this effect involves prevention of ischaemia-induced leukocytosis[3].
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