Lanosterol
CAS No. : 79-63-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $66 | In-stock |
| 5mg | $170 | In-stock |
| 10mg | $270 | In-stock |
| 25mg | $490 | In-stock |
| 50mg | $720 | In-stock |
| 100mg | $995 | In-stock |
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| Cat. No. : | HY-W020033 |
| M.Wt: | 426.72 |
| Formula: | C30H50O |
| Purity: | >98 % |
| Solubility: | Ethanol : 3.57 mg/mL (ultrasonic);DMSO : 5 mg/mL (ultrasonic) |
Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases[1][2].
In Vitro: Lanosterol diminishes aberrant proteotoxic aggregation and mitigates their cytotoxicity via induced expression of co-chaperone CHIP and elevated autophagy[1].
Lanosterol is a precursor of meiosis-activating sterols in the cholesterol biosynthetic pathway and induces a physiological signal that instructs the oocyte to reinitiate meiosis[2].
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