Yakuchinone A
CAS No. : 78954-23-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $515 | In-stock |
| 100mg | $820 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-123386 |
| M.Wt: | 312.40 |
| Formula: | C20H24O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Yakuchinone A is a natural product isolated from the fruit of Alpinia oxyphylla, which can induce apoptosis and has anticancer and anti-inflammatory activities[1].
In Vitro:Yakuchinone A acts on A375P, B16F1, B16F10, A549, MCF-7 and HT-29 cell lines with the IC50 values of 14.75, 31.73, 21.71, 26.07, 11.50 and 11.96 μM, respectively[1].
Yakuchinone A (0-64 μM, 16 h) can reduce IL-17 production in a dose-dependent manner and the IC50 value is 11.5 μM in EL4 (a mouse lymphoma cell line) cells[2].
In Vivo:Yakuchinone A (50 mg/kg, i.p., daily, 14 days) can reduce the symptoms of EAE in mice in autoimmune encephalomyelitis (EAE) mouse model[1].
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