3β-Ursodeoxycholic acid


CAS No. : 78919-26-3

(Synonyms: Isoursodeoxycholic acid)

78919-26-3
Price and Availability of CAS No. : 78919-26-3
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10mg $170 In-stock
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Cat. No. : HY-113478
M.Wt: 392.57
Formula: C24H40O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 78919-26-3 :

3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid shows good tolerance and well intestinal absorption by oral adminstation. 3β-Ursodeoxycholic acid can be isomerized by intestinal and hepatic enzymes to yield UDCA[1]. In Vitro:3β-Ursodeoxycholic acid (100 μM) reveals cytoprotective effects towards ethanol-induced cell injuries in HepG2 cells[1].
In Vivo:3β-Ursodeoxycholic acid (2.5 g/kg, p.o. for 3 weeks) converts in the liver to ursodeoxycholic acid (UDCA) in bile duct ligated rats, features UDCA pro-drug characteristics[2].

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