TDP-665759
CAS No. : 787632-66-0
Price and Availability of
CAS No. : 787632-66-0
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|---|---|---|
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| 500 mg | Get quote | |
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| Cat. No. : | HY-18329 |
| M.Wt: | 706.44 |
| Formula: | C31H34Cl2IN5O2 |
| Purity: | >98 % |
| Solubility: |
Introduction of
787632-66-0
:
TDP-665759 is an inhibitor for HDm2:p53 complex, and thus activates p53, inhibits STAT3 signaling pathway (EC50 of 5.90 μM) and the cell viability of p53 expressing A549R (IC50 of 7.02 μM). TDP-665759 induces apoptosis in HepG2. TDP-665759 exhibits antitumor efficacy in mouse models[1].
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- TDP-665759
- Cat. No.:
- HY-18329
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