D-AP4
CAS No. : 78739-01-2
(Synonyms: D-APB; D-2-Amino-4-phosphonobutyric acid)
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| Cat. No. : | HY-100781 |
| M.Wt: | 183.10 |
| Formula: | C4H10NO5P |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co2+ influx in cultured cerebellar granule cells (IC50 ≥ 100 μM)[1][2][3].
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