SB772077B
CAS No. : 785774-34-7
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| Cat. No. : | HY-123958 |
| M.Wt: | 342.36 |
| Formula: | C15H18N8O2 |
| Purity: | >98 % |
| Solubility: |
SB772077B is a ROCK inhibitor. SB772077B has an anti-inflammatory activity and enhances aqueous outflow facility (OF) by inactivating RhoA/ROCK signal pathway. SB772077B significantly reduces the mRNA level of β-catenin and protein level of fibrotic markers, such as vinculin, fibronectin, collagen 1 A and vimentin. SB772077B also has vasodialatory activity and decreases pulmonary and systemic blood pressure. SB772077B can be used for glaucoma research and pulmonary hypertensive disorder research[1][2].
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