BMY-25271
CAS No. : 78441-82-4
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| Cat. No. : | HY-100191 |
| M.Wt: | 329.44 |
| Formula: | C12H19N5O2S2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
BMY-25271 is a histamine H2 receptor antagonist. IC50 & Target: Histamine H2 receptor[1] In Vivo: BMY-25271 is a histamine H2 receptor antagonist. The dose response curves are parallel and oral ED50 values derived from probit analysis are 0.093, 0.97 and 6.9 mg/kg for BMY-25271, ranitidine and cimetidine, respectively. BMY-25271, therefore, is about 10 and 74 times more potent than ranitidine and cimetidine, respectively. Pretreatment with the highest dose of BMY-25271 does not significantly affect the absorption of aspirin or the formation of its major metabolite, salicylic acid[1].
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