Ceftazidime (pentahydrate)


CAS No. : 78439-06-2

(Synonyms: GR20263 (pentahydrate))

78439-06-2
Price and Availability of CAS No. : 78439-06-2
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Cat. No. : HY-B0593A
M.Wt: 636.65
Formula: C22H32N6O12S2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 78439-06-2 :

Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases[1]. In Vitro: Ceftazidime (0-8 µg/mL approximately, 24 h) pentahydrate displays antibacterial and anti-biofilm activities against P. aeruginosa strains[2].
Ceftazidime (0-40 µg/mL approximately, 18-20 h) pentahydrate has inhibitory activities against S. maltophilia isolates[3].
In Vivo: Ceftazidime (2 h infusion of injection, 2 000 mg, every 8 h for 24 h) pentahydrate moderately reduces bacterial density in a murine thigh infection model[4].

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