Linalool,98% (stabilized with MEHQ)
CAS No. : 78-70-6
| Size | Price | Stock |
|---|---|---|
| 10g | $5 | In-stock |
| 100g | $17 | In-stock |
| 500g | $27 | In-stock |
| 1000g | $53 | In-stock |
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| Cat. No. : | HY-N0368 |
| M.Wt: | 154.25 |
| Formula: | C10H18O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities[1][2][3][4][5].
In Vitro:Linalool (0-2000 μM, 24-72 h) can induce apoptosis of cancer cells (U87-MG, HepG-2, SW620 and so on) through oxidative stress while protecting normal cells PC12[3].
Linalool (0-2000 mg/mL, 0-72 h) exerts antibacterial effects by damaging cell membranes[3].
Linalool (0-2 mM, 24-48 h) inhibits A549 cell proliferation by inducing G0/G1 and/or G2/M cell cycle arrest, and without affecting the cell viability of normal lung WI-38 cells. Linalool inhibits A549 cell migration[4].
In Vivo:Linalool (150, 200, 250 mg/kg orally every alternate day for 21 days) reduces tumor growth by 50% in the S-180 solid tumor mouse model, inhibits oxidation in normal liver, and promotes oxidation in tumor tissue[5].
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