Dermorphin
CAS No. : 77614-16-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $256 | In-stock |
| 50mg | $360 | In-stock |
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| Cat. No. : | HY-P0244 |
| M.Wt: | 802.87 |
| Formula: | C40H50N8O10 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 100 mg/mL |
Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Inhibition of neuropathic pain[1]. IC50 & Target: μ-opioid receptor (MOR)[1] In Vitro: Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor[2].
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