Tetraethylene glycol monotosylate


CAS No. : 77544-60-6

(Synonyms: Tos-PEG4)

77544-60-6
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Cat. No. : HY-41541
M.Wt: 348.42
Formula: C15H24O7S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 77544-60-6 :

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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