Corylifol A


CAS No. : 775351-88-7

(Synonyms: Corylifol-A; Corylinin)

775351-88-7
Price and Availability of CAS No. : 775351-88-7
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1mg $60 In-stock
5mg $120 In-stock
10mg $190 In-stock
25mg $380 In-stock
50mg $608 In-stock
100mg $970 In-stock
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Cat. No. : HY-N0897
M.Wt: 390.47
Formula: C25H26O4
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 775351-88-7 :

Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC50 of 0.81 μM. IC50 & Target: IC50: 0.81 uM (STAT3)[1]. In Vitro: Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 0.81±0.15 μM, also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells[1]. Corylifol A inhibits SARA PLpro in a dose-dependent manner with IC50s ranging between 4.2 and 38.4 μM[2]. Corylifol A is found to be a naturally occurring potent inhibitor of hCE2, with low Ki values ranging from 0.62 μM to 3.89 μM[3].

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