Anecortave acetate
CAS No. : 7753-60-8
(Synonyms: Anecortave)
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| Cat. No. : | HY-116868 |
| M.Wt: | 386.48 |
| Formula: | C23H30O5 |
| Purity: | >98 % |
| Solubility: | Methanol : 1 mg/mL (ultrasonic) |
Anecortave acetate is a potent ocular angiostatic agent. Anecortave acetate inhibits neovascularization which is induced by many different angiogenic factors, and increases plasminogen activator inhibitor-1 (PAI-1) mRNA expression. Anecortave acetate can be used to research ocular neovascular diseases[1][2]. IC50 & Target:PAI-1[2] In Vivo:Anecortave acetate (5 μl of a 10% suspension; Injected into eyes) significantly inhibits pathologic retinal angiogenesis and increases PAI-1 mRNA levels[2].
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