Phenylpiracetam
CAS No. : 77472-70-9
(Synonyms: Carphedon)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $60 | In-stock |
| 50mg | $80 | In-stock |
| 100mg | $90 | In-stock |
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| Cat. No. : | HY-14840 |
| M.Wt: | 218.25 |
| Formula: | C12H14N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Phenylpiracetam (Carphedon) is a positive allosteric modulator of nicotinic acetylcholine receptors (nAChR) with an IC50 of 5.86 μM. Phenylpiracetam is applicable to studies on scopolamine (Scopolamine) (HY-N0296)-induced amnesia, depression and immune stress[1][2].
In Vitro:Phenylpiracetam directly interacts with mouse brain cortex α4β2 nicotinic acetylcholine receptors with an IC50 of 5.86 μM[1].
In Vivo:Phenylpiracetam (100 mg/kg; i.p.; single dose) attenuates scopolamine-induced amnesia in male Wistar rats by normalizing densities of striatal D1, cortical nicotinic acetylcholine, and cortical benzodiazepine receptors, partially reducing hippocampal NMDA receptor density, and increasing striatal D2 receptor density by 29% relative to controls[1].
Phenotropil (25 mg/kg; i.p.; daily; 5 days) exerts a strong psychoimmunomodulatory effect in LPS-induced immune stress in Wistar rats, normalizing key cellular and innate immune parameters while improving locomotor, exploratory, and anxiety-related behaviors without altering antibody production[2].
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