SL 0101-1
CAS No. : 77307-50-7
(Synonyms: SL0101)
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| 5mg | $396 | In-stock |
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| Cat. No. : | HY-15237 |
| M.Wt: | 516.45 |
| Formula: | C25H24O12 |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic;warming) |
SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM[1]. SL 0101-1 (SL0101) is a selective RSK1/2 inhibitor, with a Ki of 1 μM[2].
IC50 & Target:IC50: 89 nM (RSK)[1].
Ki: 1 μM (RSK1/2)[2].
In Vitro: SL 0101-1 (SL0101) shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase[1].
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