(R)-Azetidine-2-carboxylic acid
CAS No. : 7729-30-8
| Size | Price | Stock |
|---|---|---|
| 250mg | $14 | In-stock |
| 1g | $18 | In-stock |
| 5g | $73 | In-stock |
| 10g | $143 | In-stock |
| 25g | $353 | In-stock |
| 100g | $1226 | Get quote |
| 200 g | Get quote | |
| 500 g | Get quote | |
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| Cat. No. : | HY-W017755 |
| M.Wt: | 101.10 |
| Formula: | C4H7NO2 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 175 mg/mL |
(R)-Azetidine-2-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (R)-Azetidine-2-carboxylic acid is also a alkyl chain-based PROTAC linker that can be
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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- Cat. No.:
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