Glufosinate (ammonium)
CAS No. : 77182-82-2
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| Cat. No. : | HY-W019870 |
| M.Wt: | 198.16 |
| Formula: | C5H15N2O4P |
| Purity: | >98 % |
| Solubility: | H2O : 250 mg/mL (ultrasonic) |
Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium exerts neurotoxic activity[1][2].
In Vitro: Glufosinate ammonium (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs)[2].
Glufosinate ammonium (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM[2].
Glufosinate ammonium impairs ependymal cell capability to synthetize cilia[2].
In Vivo: Glufosinate ammonium (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats[3].
The Elimination of Glufosinate ammonium (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats[3].
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