Flaconitine
CAS No. : 77181-26-1
(Synonyms: Acetylaconitine; 3-Acetylaconitine)
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $135 | In-stock |
| 50mg | $340 | In-stock |
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| Cat. No. : | HY-N0276 |
| M.Wt: | 687.77 |
| Formula: | C36H49NO12 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Flaconitine is considered to be a NF-κB inhibitor. IC50 & Target: NF-κB[1] In Vitro: Flaconitine has been demonstrated to suppress TNF-α induced NF-κB activation and is considered as a diester-diterpenoid-type NF-κB inhibitor[1] Flaconitine (3-Acetylaconitine) is evaluated for its cytotoxic activity against human leukemic P388 cells using the SRB (Sulforhodamine B) method, with Etoposide as the positive control. The cell growth inhibitory potency of Flaconitine is expressed as IC50 (μM) Value. Flaconitine exhibits moderately cytotoxic activity with an IC50 of 18.6 μM[2].
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