DL-Allylglycine
CAS No. : 7685-44-1
(Synonyms: 2-Aminopent-4-enoic acid)
| Size | Price | Stock |
|---|---|---|
| 1g | $17 | In-stock |
| 5g | $42 | In-stock |
| 10g | $53 | In-stock |
| 25g | $103 | In-stock |
| 100g | $356 | In-stock |
| 500g | $1779 | In-stock |
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| Cat. No. : | HY-W023493 |
| M.Wt: | 115.13 |
| Formula: | C5H9NO2 |
| Purity: | >98 % |
| Solubility: | H2O : 5.56 mg/mL (ultrasonic) |
DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures[1][2].
IC50 & Target:Glutamate Decarboxylase (GAD)[1]
In Vivo:DL-Allylglycine (0.8 mmol/kg, i.p., single dose) significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity[1].
DL-Allylglycine (30-40 mg/kg, i.v., once) induces stable photosensitivity with photically induced seizures in lateral geniculate body (GL)-kindled cats[2].
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