Myxothiazol
CAS No. : 76706-55-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $390 | In-stock |
| 5mg | $1100 | In-stock |
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| Cat. No. : | HY-112177 |
| M.Wt: | 487.68 |
| Formula: | C25H33N3O3S2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml[1][2].
In Vitro:Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml[2].
Myxothiazol binds to the ubiquinol oxidation site Qo of complex III and blocks electron transfer from ubiquinol to cytochrome b and thus inhibits complex III activity[3].
In Vivo:Myxothiazol (i.p.; 0.56 mg/kg; daily for 4 days)-induced complex III inhibition can be induced in mice for four days in a row without overt hepatotoxicity or lethality[3].
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- Cat. No.:
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