Detomidine
CAS No. : 76631-46-4
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| Cat. No. : | HY-B0163 |
| M.Wt: | 186.25 |
| Formula: | C12H14N2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects[1][2]. In Vitro: Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.
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