Azamulin
CAS No. : 76530-44-4
| Size | Price | Stock |
|---|---|---|
| 500μg | $110 | Get quote |
| 1mg | $180 | In-stock |
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| 10 mg | Get quote | |
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| Cat. No. : | HY-W019847 |
| M.Wt: | 478.65 |
| Formula: | C24H38N4O4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Azamulin is an irreversible, highly selective inhibitior of human CYP3Aa. Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM. Azamulin can be used for the research of metabolism and antiinfection[1].
IC50 & Target:IC50: 0.03-0.24 μM (CYP3A)[1]
In Vitro:Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM[1].
Azamulin has CYP3A inhibition appeared sigmoidal and well behaved with the substrates 7-benzyloxy-4-trifluoromethylcoumarin, testosterone, and midazolam[1].
Azamulin (4.8 μM；10 min) inhibits approximately 95% of testosterone 6beta-hydroxylase activity in the presence of NADPH[1].
Azamulin exhibits good chemical stability when stored in acetonitrile for up to 12 days[1].
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