Fosalvudine tidoxil
CAS No. : 763903-67-9
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| Cat. No. : | HY-14922 |
| M.Wt: | 722.93 |
| Formula: | C35H64FN2O8PS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Fosalvudine tidoxil is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Fosalvudine tidoxil is a prodrug derived from Alovudine (HY-B1516). Fosalvudine tidoxil is less toxic than Alovudine and can be used for the research of HIV-1 infection[1]. IC50 & Target:Nucleoside reverse transcriptase[1] In Vivo:Fosalvudine tidoxil (15-100 mg/kg/day; oral; 8 weeks) induces significant mitochondrial hepatotoxicity in rats[1].
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